Linker 101- Examining the Importance of Linker Stability

Time: 9:01 am
day: Pre-Conference Workshop Day


With an increasing abundance of ADCs entering preclinical and clinical studies, the amount of information ADC developers are collecting about when to use what linker is growing. Additionally, as the ADC design toolkit expands, selecting the right linker for your desired ADC is becoming a key strategic design talking point.

Attending this workshop will provide a high-level overview of the current linker technologies available to enable you to:

• Learn the basics of linker chemistry and examine how it can be modified to create a linker with optimal properties for you desired outcome

• Understand why selecting the correct linker is integral to your ADC’s success, and evaluate the advantages of using different linkers in different settings

• Compare and contrast cleavable and non-cleavable linkers and analyze how payload choice affects your linker choice