Mark Distefano
Professor University of Minnesota
Seminars
Thursday 21st August 2025
Protein Conjugation Beyond Maleimide – Exploring Protein Functionalization Using Prenyltransferases
9:00 am
- Prenyltransferases can be used to install a wide variety of biorthogonal functionality in proteins
- That functionality can be used to create protein conjugates for a range of applications ranging from directed cell killing to PET imaging
- Prenyltransferases can also be used to create prenylated nanostructures that can be positioned on the surfaces of cells to transfer a variety of cargos to specific receiver cells
