7:50 am Check-In & Morning Coffee
8:50 am Chair’s Opening Remarks
Exploring Novel ADC Linker & Conjugation Technologies to Usher in the Next-Generation of ADCs & Increase Efficacy
9:00 am Developing the Next Generation of ADCs With High DAR & Dual Payloads to Enhance ADC Efficacy
9:30 am EZWi-Fit, A Novel Linker-Toxin Platform That Confers ADC With Improved Efficacy & Safety
10:00 am Development of a site specific and versatile conjugation approach based on bacterial transglutaminase and the Diels-Alder cycloaddition reaction for ADCs
10:30 am Morning Break & Speed Networking
Synopsis
This is an informal session to help you connect with your peers in a relaxed atmosphere and continue forging new and beneficial relationships. You will have the opportunity to present your work, and review presentations displaying novel approaches and findings.
Exploring Stability Within ADC Linkers & Conjugations to Reduce off Target Toxicities While Ensuring Accurate Payload Release
11:30 am Exploring Novel Linker Chemistries to Improve the Therapeutic Index
12:00 pm Talk Reserved for Paul Davis
12:30 pm Networking Lunch
Addressing the Never-Ending Battle of Cleavable vs Non-Cleavable Linkers to Select the Most Appropriate One for Your ADC
1:30 pm Roundtable Discussion – Is a Linker That is Too Stable a Problem & How Do We Overcome That?
2:00 pm Exploring Click-Cleavable ADCs & Their Application Scope
2:30 pm Understanding How to Tune the Cleavage Rate of Linkers to Increase Specificity Towards Tumor Microenvironments
3:00 pm Chair’s Closing Remarks
3:05 pm Scientific Poster Session
Synopsis
This is an informal session to help you connect with your peers in a relaxed atmosphere and discuss novel linker & conjugation technologies and their challenges. You will have the opportunity to present your work, and review presentations displaying novel approaches and findings.
4:05 pm End of Scientific Program Day One
