Philipp Spycher

Chief Scientific Officer & Co-Founder Araris Bio

Seminars

Wednesday 20th August 2025
Designing Branched Linkers for Dual Payload ADCs to Balance Synergy & Selectivity
9:30 am
  • Investigating chemical engineering strategies for designing branch linkers for achieving distinct tumor-specific cleavage mechanisms
  • Addressing challenges in maintaining payload stability and ensuring effective payload release while preserving the overall functionality of the ADC
  • Exploring the use of modified conjugation methods to achieve controlled ratios of each payload, ensuring synergistic effects without compromising safety or efficacy
Philipp Spycher - 3rd ADC Linker & Conjugation Summit