Nathan Tumey

Company: Binghampton University

Job title: Assistant Professor

Seminars:

Looking Beyond Cathepsins: Understanding & Optimizing Legumain- Cleavable ADC Linkers 2:00 pm

• Overviewing the development of peptide libraries screened to identify new ADC linkers • Demonstrating mechanism of legumain-cleavable linkers • Learning functional and biophysical differentiation of legumain-cleavable linkers from cathepsin-cleavable linkersRead more

day: Scientific Program Day 1

Delving Into Site-Specific Conjugations to Create Homogenous ADCs 1:01 pm

In the last two years, the proportion of clinically site-specific ADC has increased from 23% to 29%*, and novel site-specific conjugation technologies have overtaken traditional cysteine-based site-specific ADCs. This has given food for thought to ADC developers on what conjugation strategies to employ. It has also made assessing the advantages of site-specific conjugation versus stochastic…Read more

day: Pre-Conference Workshop Day