Sara Wichner

Sara Wichner is a Scientist 4 in the Protein Chemistry department at Genentech, where she specializes in antibody-drug conjugate (ADC) design, bioconjugation, and physicochemical characterization. Since joining Genentech in 2016, she has advanced through scientific leadership roles, focusing on linker-drug optimization, high-DAR conjugate development, and the validation of emerging analytical technologies including mass photometry. Sara holds a Ph.D. from UC Berkeley, where she worked with Prof. Ahmet Yildiz, and completed her undergraduate training at the University of Chicago. She was also a summer intranural at the National Cancer Institute. Sara has presented previously at the ADC Linker & Conjugation Summit and returns to share new data on intelligent linker-drug design for DAR ≥8, non-aggregated ADCs.