Leveraging Linker Design & Drug Developability Assessment to Develop Successful ADCs

Time: 10:00 am
day: Conference Day One

Details:

  • Explore how ADC linkers represent more than a bridge between the antibody and payload, allowing to modulate ADCs’ biological activity
  • Discuss how identifying the best combination of antibody, linker and payload is a challenge that can be overcome by applying stage-specific evaluation criteria to de-risk ADC candidate selection
  • Review case studies showing how to construct and evaluate appropriate ADC candidate matrices, varying payloads, and linker elements for lead candidate selection