Optimizing Site-Specific Conjugations to Control Conjugation Process & Produce Homogeneous DAR

Time: 9:00 am
day: Conference Day Two

Details:

  • Explore site specific conjugation: the patented « Q-Tag » sequence insertion that allows to precisely defined location of the selected payload on the antibody
  • Assess Mab design versatility: Transglutaminase based methods that can be applied to a variety of antibody formats (Full length, Fab, scfv, VHH…) and/or payloads (drug, radioelements, dyes…)
  • Evaluate better penetration for solid tumor: FDCs are smaller than full-length antibodies, exhibiting therefore higher tissue penetration, with better drug delivery to the target site

Speakers: